XEOMIN® (incobotulinumtoxinA) includes a prescription medication that we can inject into muscles. We use it to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults. It contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum.
When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines. Botulinum toxin type A – the active ingredient in XEOMIN®– acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, it can temporarily reduce the lines between your eyebrows.
The treatment itself usually only takes about 10 to 20 minutes. First, our nurse will inject the product into the muscles in your forehead that cause frown lines between your eyebrows. It requires no anesthesia. Afterward, you may begin to see visible smoothing as early as three to four days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days.
The typical duration of effect was up to 3 months in clinical trials. However, results may last significantly longer or shorter in individual patients.